The 2024 NFL schedules were released on Thursday and sportsbooks have already posted betting odds for Week 1. There are some marquee matchups starting with the Baltimore Ravens visiting the Kansas City Chiefs on Thursday Night Football. 

Here is an early look at all the Week 1 matchups with spreads, totals and predictions for every game. 

NFL Week 1 betting odds

Odds courtesy of DraftKings Sportsbook

Baltimore Ravens at Kansas City Chiefs (-3, 47.5)

The NFL season kicks off with a bang on Thursday, Sept. 5 with a rematch of the AFC Championship Game. The Ravens will unleash their new-look backfield featuring a slimmed down Lamar Jackson and newly acquired Derrick Henry. 

Rashee Rice could be facing a suspension and with his status in doubt, I like Baltimore getting a field goal. Look for this line to drop as we get closer to kickoff. 

Green Bay Packers vs. Philadelphia Eagles (-1.5)

This game is being played on Friday in Brazil. The Eagles floundered down the stretch last season but brought in a lot of new faces, especially on the defensive side of the ball. The Packers are a sexy pick to make the Super Bowl after last year’s strong finish and upset over the Cowboys in the playoffs. 

Keep in mind though, Green Bay is still very young and I expect the Eagles to come out strong after last season’s collapse. I like Philadelphia to cover the short number on a neutral field. 

Carolina Panthers at New Orleans Saints (-4.5, 42)

I don’t see any reason to be high on the Panthers. Nothing Carolina did this offseason screams major improvement. Look for the Saints to cruise to a double-digit win in the season opener. 

WATCH: Previewing the Saints’ brutal schedule

Jacksonville Jaguars at Miami Dolphins (-4, 49.5)

Last season, the Dolphins beat up on bad teams and lost to good teams. But what category are the Jaguars in? 

Jacksonville is one of the toughest teams for me to get a grasp on heading into the season. I lean Miami but it’s not one of my favorite Week 1 plays. 

Arizona Cardinals at Buffalo Bills (-7, 48.5)

I love the Cardinals in this spot. Arizona has drafted well the last two offseasons and I think we start seeing that improvement on the field. 

The Bills lost Stefon Diggs and will feature a lot of new faces heading into Week 1. Buffalo may prevail at home but I’ll take the Cardinals to cover the seven points. 

Minnesota Vikings at New York Giants (-1, 41.5)

I don’t have a strong opinion on this game. Two unknown teams because of questions at the quarterback position. The Giants will try to win games with defense and not turning the ball over. I expect a lower scoring game here. 

New England Patriots at Cincinnati Bengals (-7.5, 44)

The Patriots aren’t projected to be very good with a win total of 4.5 but remember, New England returns a very good defense from last season. Week 1 is now like extended preseason with defenses having an edge. Bengals should get the win at home but I lean under 44.5 points. 

Tennessee Titans at Chicago Bears (-4, 43.5)

There is a lot of hype surrounding the Bears entering the season after drafting Caleb Williams and Rome Odunze, along with signing veteran WR Keenan Allen.

While Chicago is certainly improved, I actually like what Tennessee has done. A strong draft and key free agent additions makes the Titans an intriguing sleeper in the AFC South.

I like taking the points here even though I think both teams will be much-improved this season. 

Houston Texans (-1.5, 47.5) at Indianapolis Colts 

A lot of people are on Houston after the Texans added veterans Joe Mixon and Stefon Diggs to an already strong roster. I’m one of those peoples.

Houston is the only road favorite in Week 1 but I expect CJ Stroud to cover the short number in what should be one of the better games on opening Sunday. 

Pittsburgh Steelers at Atlanta Falcons (-2.5, 45)

This is one of the toughest Week 1 games to call. We know the Steelers’ defense will be strong but can the offense improve with Russell Wilson? 

Quarterback is one position Atlanta doesn’t need to worry about considering they now have something like six starters after signing Kirk Cousins and drafting Michael Penix Jr. I lean the Falcons at home. Just can’t trust the Steelers until I see Wilson in that offense. 

Washington Commanders at Tampa Bay Buccaneers (-4.5, 40.5)

Ironically, these are two teams I like to surprise in the NFC. People are sleeping on Tampa Bay a little bit and the revamped Commanders should be miles better this year.

My initial thinking is taking the 4.5 with Washington. I expect rookie quarterback Jayden Daniels to be good right away and could see the Commanders pulling the outright upset in Week 1. 

Dallas Cowboys at Cleveland Browns (-1, 44.5)

The featured late game on opening Sunday pits the Cowboys traveling to Cleveland with Tom Brady making his broadcast debut with Fox. This is a tough first-game draw for Dallas. The Cowboys could be starting two rookie offensive linemen against arguably the best defensive front in the NFL. 

Look for Myles Garrett to get off to a strong start in his quest to win back-to-back Defensive Player of the Year awards. The Browns laying a short number at home is one of my favorite Week 1 bets. 

Las Vegas Raiders at Los Angeles Chargers (-2.5, 44)

I like the Raiders getting points here. Jim Harbaugh will turn the Chargers around but it will take a minute until he builds up the offensive and defensive lines. Las Vegas has a sneaky good defense and I see the Raiders stealing the opener on the road. 

Denver Broncos at Seattle Seahawks (-4.5, 44)

I have a lot of respect for Sean Payton as a head coach but I expect the Broncos to suffer through another long season. I just don’t see an immediate answer at quarterback even if rookie Bo Nix starts. I’ll lay the points with Seattle at home. 

Los Angeles Rams at Detroit Lions (-3, 50.5)

Sunday Night Football kicks off with a barn burner. Like many other analysts, I’m high on both of these teams. However, I’m higher on the Lions. Detroit is loaded and I think they make a statement at home in Week 1. 

New York Jets at San Francisco 49ers (-5.5, 46.5)

The Jets will start their season on Monday night for the second-straight year. Aaron Rodgers is hoping things go better this time around after tearing his Achilles just three plays into the 2023 season. 

The thing that stands out to me in this matchup is the total. I think 46.5 is too high in a game that features two of the NFL’s top defenses. The focus will be on Rodgers’ return but taking the under in Jets games this season should be a profitable venture.  

Best Bets

Browns -1

Eagles -1.5

Cardinals +7

Lions -3